EPITHALON

Description
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EPITHALON

Epithalon (also known as Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) modeled after a natural peptide produced in the pineal gland. In gerontological research, it is primarily studied for its ability to induce the expression of the enzyme telomerase. Laboratory investigations focus on its influence on telomere maintenance, its role in regulating melatonin secretion, and its impact on the suppression of cellular senescence markers in aging models.

For Research Use Only.

Core Science and Mechanism

Telomere Maintenance: Modeled on a pineal gland extract called epithalamin, it is researched for stimulating telomerase activity to lengthen or preserve chromosomal telomeres. [1, 2, 3]

Circadian Support: Targets the neuroendocrine system to potentially normalize melatonin production and improve sleep quality. [1, 2]

Pioneering Research: Developed originally by Russian gerontologist Vladimir Khavinson, though long-term, independently replicated human clinical trials remain limited. [1, 2]

Administration and Status

Usage Patterns: Administered via subcutaneous injection in short cycles (such as 5 to 10 mg daily for 10 to 20 days) rather than continuous use. [1, 2]