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LL-37

LL-37

Original price was: $107.00.Current price is: $90.00.

Category: Uncategorized Tags: ll 37 peptide, LL-37, peptide ll-37

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LL-37

LL-37 is a 37-amino acid antimicrobial peptide (AMP) belonging to the cathelicidin family. In biochemical research, it is studied for its multifaceted role in the innate immune response, including its ability to neutralize lipopolysaccharides (LPS) and promote wound healing pathways. Laboratory investigations often center on its antimicrobial properties and its influence on cell migration.

LL-37 is a naturally occurring human peptide that acts as the only member of the cathelicidin antimicrobial family, key features include broad-spectrum defense, immune modulation, and tissue repair. It serves as a first-line defense molecule produced by immune and epithelial cells. [1, 2, 3, 4]

Biological Functions

Antimicrobial action: Kills bacteria, fungi, and viruses by disrupting their cell membranes.

Biofilm disruption: Breaks down protective bacterial layers to help clear resistant strains.

Immune regulation: Attracts immune cells to sites of infection and controls inflammation levels.

Wound healing: Stimulates blood vessel growth and tissue regeneration. [1, 2, 3, 4]

Research and Medical Context

Not approved: LL-37 is not approved by regulatory agencies like the FDA for routine clinical use or treatment.

Autoimmunity links: Abnormal levels or activity are studied in connection with inflammatory diseases like psoriasis and lupus.

Laboratory status: Current usage remains strictly experimental for scientific and medical research. [1, 2, 3, 4]

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