SLU-PP-332
SLU-PP-332 is a non-peptide small molecule that functions as a potent, selective Estrogen-Related Receptor (ERR) agonist, specifically targeting the ERRα, ERRβ, and ERRγ isoforms. In metabolic research, it is utilized as an exercise mimetic to study the upregulation of mitochondrial genetic programs. Laboratory studies focus on its ability to enhance oxidative capacity in skeletal muscle, improve metabolic flexibility, and stimulate the expression of genes involved in fatty acid oxidation.
- Metabolic Mimicry: Triggers the same genetic pathways in skeletal muscle that the body normally activates during endurance or aerobic exercise. [1]
- Animal Studies Only: Proven in laboratory mice to reduce fat mass, enhance treadmill endurance by nearly 50%, and improve insulin sensitivity in metabolic syndrome models.
- No Human Trials: There are no completed human clinical trials, and safety or side effect profiles in people remain entirely unknown.
- Preclinical Tool: Classified strictly as a research compound and chemical probe, not an approved medication or dietary supplement.















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